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The Environmental Protection Agency (EPA) has not conducted a
recent evaluation of demand for Integrated Risk Information System
(IRIS) toxicity assessments with input from users inside and
outside EPA. The health effects information in IRIS provides
fundamental scientific information EPA needs to develop human
health risk assessments. Specifically, EPA issued a needs
assessment report in 2003, which estimated that 50 new or updated
IRIS toxicity assessments were needed each year to meet users'
needs. This book determines the extent to which EPA has evaluated
demand for IRIS toxicity assessments from users inside and outside
EPA; EPA's process for nominating and selecting chemicals for IRIS
toxicity assessment and strategies for addressing any unmet agency
needs when IRIS toxicity assessments are not available, applicable,
or current.
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